Document Type

Article

Publication Date

1-2020

MeSH Terms

MicroRNA, Forensic Sciences, Body Fluids

Subject: LCSH

MicroRNA, Forensic Sciences, Body Fluids,

Disciplines

Forensic Science and Technology

Abstract

Within the forensic science community, there is a continued push to develop novel tools to aid in criminal investigations. microRNA (miRNA) analysis has been the focus of many researcher’s attention in the biomedical field since its discovery in 1993; however, the forensic application of miRNA analysis has only been suggested within the last 10 years and has been gaining considerable traction recently. The primary focus of the forensic application of miRNA analysis has been on body fluid identification to provide confirmatory universal analysis of unknown biological stains obtained from crime scenes or evidence items. There are, however, other forensic applications of miRNA profiling that have shown potential, yet are largely understudied, and warrant further investigation such as organ tissue identification, donor age estimation, and more. This review paper aims to evaluate the current literature and future potential of miRNA analysis within the forensic science field.

Comments

© 2020 Glynn; Published by Cold Spring Harbor Laboratory Press for the RNA Society

This article is distributed exclusively by the RNA Society for the first 12 months after the full-issue publication date (see http://rnajournal.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/. This license permits non-commercial use, including reproduction, adaptation, and distribution of the article provided the original author and source are credited.

Article is online at http://www.rnajournal.org/cgi/doi/10.1261/rna.072173.119.

DOI

10.1261/rna.072173.119

Creative Commons License

Creative Commons Attribution-NonCommercial 4.0 International License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License

Publisher Citation

REVIEW: Potential applications of microRNA profiling to forensic investigations Claire L. Glynn RNA January 2020 26: 1-9; Published in Advance October 28, 2019, doi:10.1261/rna.072173.119

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