Document Type

Article

Publication Date

9-12-2019

MeSH Terms

Forensic Sciences, Forensic Genetics, DNA,Y Chromosome, Haplotypes

Subject: LCSH

Forensic Sciences, Forensic Genetics, DNA, Y Chromosome

Disciplines

Forensic Science and Technology

Abstract

Forensic haplotype analysis of the male Y chromosome is currently used to establish the number of male donors in sexual assaults, the number of male bleeders in blood pattern analysis, and for ancestry correlation to genetic founder populations in biogeographic studies. In forensic laboratory applications, its primary use is for DNA profile generation with trace amounts of male DNA in the presence of excess female DNA (e.g. spermatozoa identification, male component of fingernail scrapings). Our study supports the potential use of the Y chromosome in a “dragnet” approach (most haplotypes are unique) similar to that described by Kayser in 2017 for solving a cold case sex assault and homicide in The Netherlands. Our study also researched the potential for the identification of an ancestral Irish genetic “footprint” linked to surname O’Brien and identified multiple founder group origins in Ireland and England as well as three samples with the Dal Riata (a Gaelic overkingdom) ancestral haplotype. This study indicates correlation to ancestral Irish ancestry by haplotype but not conclusively to the O’Brien surname.

Comments

© 2019 The Author(s). Published by Taylor & Francis Group on behalf of the Academy of Forensic Science. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The article originally appeared in the journal, Forensic Sciences Research, and is available from the publisher's website.

DOI

10.1080/20961790.2019.1639881

Creative Commons License

Creative Commons Attribution 4.0 License
This work is licensed under a Creative Commons Attribution 4.0 License.

Publisher Citation

Robert Whiting & Heather Miller Coyle (2019) Haplotype analysis for Irish ancestry, Forensic Sciences Research, DOI: 10.1080/20961790.2019.1639881

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.